Conveners
Radiotherapy and Radiobiology
- Jeffrey Crosbie ()
Dr
Helen Forrester
(Hudson Institute of Medical Research)
26/11/2015, 11:00
Radiotherapy and Radiobiology
Oral
Microbeam radiotherapy (MRT) utilizes high intensity synchrotron generated X-rays collimated planar microbeams (~25 µm). MRT showns promise for cancer treatment, effectively ablating tumours while causing less normal tissue damage compared to conventional broadbeam (BB) radiotherapy. Synchrotron radiation also has low scattering making it ideal to investigate non-targeted, systemic radiation...
Mr
Frank Gagliardi
(William Buckland Radiotherapy Centre)
26/11/2015, 11:30
Radiotherapy and Radiobiology
Oral
Nanoparticles with high atomic number (Z) have a larger x-ray cross section than biological tissues. Synchrotron beams interact with the nanoparticles to produce Auger electrons which deposit their energy over a short range, typically less than a micron. This characteristic offers the ability to enhance the dose delivered to tumors by synchrotron broad beam (BB) or microbeam radiation therapy...
Dr
Jeffrey CROSBIE
(RMIT University)
26/11/2015, 11:50
Radiotherapy and Radiobiology
Oral
Before clinical trials of synchrotron microbeam radiotherapy (MRT) on humans can occur, a computerised treatment planning system (TPS) to calculate the dose distribution in the patient must be developed and validated. To satisfy this requirement, we use a research licenced version of the Eclipse™ TPS from Varian Medical Systems. This research license allows for customised dose calculation...
Mr
Jason Palazzolo
(Molecular Radiation Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia)
26/11/2015, 12:10
Radiotherapy and Radiobiology
Oral
Microbeam radiation therapy (MRT) is a promising modality for administering synchrotron-generated ionizing radiation (IR). Compared to conventionally used broadbeam (BB) radiation, MRT yields improved therapeutic benefits by preserving healthy tissues whilst selectively ablating tumours. By offering beam precision and reduced radiation scattering, the Australian Synchrotron (AS) is ideal for...