- Megan Maher (La Trobe University)
Dr Peter Czabotar (Walter and Eliza Hall Institute)
170. Is diffraction limited by the crystal or beam? A comparison of FEL vrs Synchrotron protein diffraction data.
Tom Caradoc-Davies (Australian Synchrotron.)
The development of X-ray Free-Electron Lasers (XFELs) has created a range of novel crystallography experiments such as the use of liquid-jet injectors. The use of goniometer-based FEL experiments(1) allows the direct comparison of diffraction from the same or similar crystals at both sources. The diffraction of a set of crystals tested on the MX2 beamline at the Australian Synchrotron and the...
Mr Lachlan Casey (University of Queensland)
The recognition of fungal effectors by plant NOD-like receptors (NLRs) is an important step in defense. The coiled-coil (CC) domains of these proteins are known to be necessary and sufficient for response. Two structures have previously been solved, which show highly divergent conformations. The CC domain of the potato NLR, Rx, adopts a compact, monomeric four-helix bundle, while that of a...
Dr Sofia Caria (La Trobe University)
Apoptosis or programmed cell death is a crucial response to perturbations in physiological conditions, allowing an organism to determine if a given cell can be eliminated when unneeded, damaged or dangerous for the organism. In this mechanism the B-cell lymphoma 2 (Bcl-2) protein family plays an important role in regulating the homeostasis . Sponges are the phylogenetically oldest...