25-27 November 2015
National Centre for Synchrotron Science
Australia/Melbourne timezone

A Feasibility Study of X-Ray Phase-Contrast Mammographic Tomography at the IMBL of the Australian Synchrotron

27 Nov 2015, 13:30
National Centre for Synchrotron Science

National Centre for Synchrotron Science

Australian Synchrotron 800 Blackburn Road Clayton VIC 3168
Board: IM-02
Poster Imaging Poster Session 2


Mr Darren Thompson (CSIRO)


We present the results of our recent experiment at the Imaging and Medical beamline of the Australian synchrotron intended to contribute to the development and implementation of low-dose, high-sensitivity 3D mammographic phase-contrast imaging, initially at synchrotrons and subsequently in hospitals and medical imaging clinics. We have tested, quantified, evaluated and optimised the effect of such imaging parameters as X-ray energy, source size, detector resolution, sample-to-detector distance, scanning and processing strategies in the case of propagation-based phase-contrast CT, using a plastic phantom simulating relevant breast tissue characteristics. The data are collected using a Hamamatsu CMOS Flat Panel Sensor, utilised in partial scan mode, with the pixel size 100µm × 100µm. Analysis of the data revealed the presence of propagation-based phase contrast and demonstrated significant improvement of the quality of phase-contrast CT imaging, compared to conventional (absorption-based) CT, at medically acceptable radiation doses.
Keywords Tomography phase-contrast synchrotron mammography

Primary author


Dr Andrew Stevenson (CSIRO) Dr Brown Jeremy (Monash University) Dr Darren Lockie (Maroondah BreastScreen) Mr Darren Thompson (CSIRO) Dr Francesco Brun (Elettra-Sincrotrone) Dr Giuliana Tromba (Elettra-Sincrotrone) Dr Konstantin Pavlov (University of New England) Marcus Kitchen (Monash University) Dr Sheridan Mayo (CSIRO) Dr Timur Gureyev (ARC Centre of Excellence in Advanced Molecular Imaging)

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