Conveners
Concurrent Session 3: Radiotherapy I
- Jeffrey CROSBIE ()
Dr
Jean-François Adam
(Université Grenoble-Alpes & Centre Hospitalier Universitaire Grenoble-Alpes)
25/11/2016, 11:00
Radiotherapy
Oral
Therapeutic applications of synchrotron x-rays are becoming a reality. The first phase I/II clinical study of Synchrotron Stereotactic Radiation Therapy (SSRT), in place at the European Synchrotron Radiation Facility (ESRF) since 2012, consists of a dose escalation protocol to show the feasibility and safety of the technique. 13 patients have been treated using 80 keV high-flux quasi-parallel...
Mr
Lloyd Smyth
(University of Melbourne, Epworth HealthCare)
25/11/2016, 11:30
Radiotherapy
Oral
Background: Diffuse Intrinsic Pontine Glioma (DIPG) is a devastating paediatric brainstem tumour with extremely poor prognosis and limited treatment options. Radiotherapy is the mainstay treatment but is limited to palliative use. Microbeam Radiotherapy (MRT) is a promising pre-clinical synchrotron radiotherapy modality which could improve the therapeutic ratio between normal tissue toxicity...
Francesca Di Lillo
(Dept. of Phys. "Ettore Pancini", University of Naples Federico II,Naples, Italy & INFN, Sez. Napoli, Italy)
25/11/2016, 11:45
Radiotherapy
Oral
In 2012, J. Boone proposed the external-beam kilovoltage radiotherapy of the breast cancer with a dedicated setup adopting an orthovoltage X-ray tube [1] rotating in full circles around the breast, with the woman in prone position. For comparison, conventional radiotherapy for breast cancer adopts a medical linac irradiating the breast with tangential beams, in supine position: the megavoltage...
Mrs
Jessica Ventura
(The Department of Obstetrics and Gynaecology, The Royal Women’s Hospital, Melbourne, VIC; Molecular Radiation Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC)
25/11/2016, 12:00
Radiotherapy
Oral
Discovery of the radiation-induced bystander effect (RIBE) demonstrates that cell death and genomic instability are not restricted to cells that are directly exposed to ionising radiation. The RIBE refers to a situation where cells that have not been directly exposed to IR behave as though they have been exposed. This phenomenon presents real clinical consequences such as increased risk of...
Prof.
Michael Lerch
(University of Wollongong)
25/11/2016, 12:15
Radiotherapy
Oral
Microbeam radiation therapy (MRT) implements spatially-fractionated kilovoltage x-rays for deep-seated tumour treatment [1,2] to provide better normal tissue sparing [3]. However, tumour treatment with MRT can be further optimized with high-Z nanoparticles (NPs), which have been shown to enhance the dose delivered by conventional radiotherapies [4]. Tantalum pentoxide (Ta2O5) NPs are novel...
