20-21 November 2014
National Centre for Synchrotron Science
Australia/Melbourne timezone
Save the date: User Meeting 2015 - 26-27 November

Correlative hydrated cellular imaging using Coherent Diffraction Imaging at the Australian Synchrotron

20 Nov 2014, 17:30
1h 30m
NCSS Exhibition Area ()

NCSS Exhibition Area

Australian Synchrotron 800 Blackburn Road Clayton VIC 3168
Board: 602


Dr Michael Jones (Australian Synchrotron; ARC Centre of Excellence for Advanced Molecular Imaging)


X-ray coherent diffractive imaging provides high resolution, high sensitivity images of intact cellular specimens without the need for sectioning, staining, or tagging. Recent advances in this field allow high resolution imaged to be obtained with a fraction of the dose than otherwise possible while increasing image quality. Further advances have pushed the technique into the X-ray water-window, opening up the possibility to image intact cellular specimens in their native hydrated environment. Here we present recent results of hydrated cellular coherent diffractive imaging, showing an unprecedented level of image quality and detail. We also outline details of the sample preparation and mounting methods for correlative imaging, together with opportunities for future development.
Keywords or phrases (comma separated) Ptychography, Cellular Imaging, Correlative Imaging

Primary author

Dr Michael Jones (Australian Synchrotron; ARC Centre of Excellence for Advanced Molecular Imaging)


Dr Grant van Riessen (La Trobe University; ARC Centre of Excellence for Coherent X-ray Science) Dr Kirstin Elgass (Monash Institute for Medical Research, Monash Micro Imaging) Dr Mark Junker (La Trobe University) Dr Martin de Jonge (Australian Synchrotron)

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