24-26 November 2021
Online
Australia/Sydney timezone

A Comparison of Different Approaches to Image Quality Assessment in Phase-Contrast Mammography

25 Nov 2021, 11:15
15m
Online

Online

Oral Biomedicine, Life science & Food Science Biomedicine, Life science & Food Science

Speaker

Jesse Reynolds (University of Canterbury)

Description

Propagation-based phase-contrast computed tomography (PB-CT) has the potential to improve breast cancer detection and characterisation compared to established mammography techniques. The aim of this work is to find a quantitative image quality metric which could accurately predict the subjective clinical image quality assessment of PB-CT images made by radiologists as described in Taba et al. [1].

The experimental data analysed in this study included PB-CT scans, which were obtained for 12 full intact mastectomy samples at Imaging and Medical beamline (IMBL) of the Australian Synchrotron at different monochromatic X-ray energies and clinically relevant radiation doses. Quantitative image quality metrics including visibility, signal to noise ratio (SNR), and spatial resolution, were calculated for all PB-CT and conventional CT image sets using the open-source 3D Slicer (https://www.slicer.org/) software. For each metric, an objective image quality “score” was generated to match the subjective scoring provided by the radiologists. Weighting factors were then applied to the scores and a weighted contrast to noise to resolution (CNR/res) score was calculated.

The unscaled contrast and spatial resolution scores were both found to have a significant correlation with the radiologists’ scores with R values of 0.9223 and 0.8360 respectively, while SNR had an insignificant correlation, with an R value of -0.6785. The weighted CNR/res score showed a significant correlation to the radiologists’ scores with an R value of 0.9681.

[1] S. T. Taba et al., Academic radiology 28.1 (2021): e20-e26.

Level of Expertise Student
Presenter Gender Man
Pronouns He/Him
Students Only - Are you interested in AINSE student funding Yes
Condition of submission Yes
Which facility did you use for your research Australian Synchrotron

Primary authors

Jesse Reynolds (University of Canterbury) Patrick Brennan TImur Gureyev (the University of Melbourne) Konstantin Pavlov

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