Ivan Kempson1, Douglass Howard1, Tyron Turnbull1
1 Future Industries Institute, University of South Australia, SA, 5095
Corresponding Author: Ivan.Kempson@unisa.edu.au
Metal nanoparticles have gained market approval for enhancing the effects of ionizing radiation in radiotherapy treatment of cancer. However the mechanism of action of metal nanoparticles exerting their effect remain...
Mucosal associated invariant T (MAIT) cells are an abundant human T cells subset that are variably activated by small-molecule metabolites presented by the MHC class 1 related molecule, MR1. During infection with riboflavin-producing microorganisms, the microbial metabolite 5-amino-6-D-ribitylaminouracil (5-A-RU) reacts with glycolysis byproducts of glyoxal/methylglyoxal forming highly potent...
To date, the COVID-19 pandemic has claimed 970,000 lives and afflicted more than 31 million individuals. Although a global effort has been enacted for vaccines and drug discovery, our rudimentary understanding of SARS-CoV-2 infection and our own immune defense against this infection remains unclear. Our immune system can naturally overcome viral infection through the presentation of viral...