2-3 December 2019
Muse
Australia/Sydney timezone

Microbial factories to complement chemical synthesis of deuterated molecules.

2 Dec 2019, 18:10
1m
Muse

Muse

18 Wally Way

Speaker

Rob Russell (ANSTO)

Description

Deuterated cholesterol is a classic example of nature providing an elegant alternative to chemical synthesis. The humble yeast used in bread and beer making has been engineered to produce pure cholesterol, which can be deuterated to varying degrees by growth on the appropriate substrates. This complements our existing capability to synthesise a specific tail-deuterated form of cholesterol for use in membrane structure and behaviour research.
The expanding range of molecules available from the National Deuteration Facility provide the contrast required for neutron, IR and NMR characterisation of complex systems. Microbial cellulose has been studied in conjunction with ionic liquids, both of which can be produced in deuterated form.
Complementing or utilising synthetically deuterated molecules, yeast and algae are recent additions to our toolbox for producing deuterated fatty acids, sterols, polysaccharides and other biopolymers.

Level of Expertise Experienced Researcher
Speakers Gender Male
Travel Funding No
Do yo wish to take part in the poster slam No

Primary authors

Rob Russell (ANSTO) Tamim Darwish (ANSTO) Dr Anwen Krause-Heuer (ANSTO)

Presentation Materials

There are no materials yet.
Your browser is out of date!

Update your browser to view this website correctly. Update my browser now

×