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SUMMARY:LCP crystallisation and its challenge with the D2L receptor
DTSTART;VALUE=DATE-TIME:20141120T063000Z
DTEND;VALUE=DATE-TIME:20141120T080000Z
DTSTAMP;VALUE=DATE-TIME:20260419T090247Z
UID:indico-contribution-704@events01.synchrotron.org.au
DESCRIPTION:Speakers: Connie Darmanin (La Trobe)\nSelf-assembly lipids hav
 e been used to solve a number of G-protein coupled receptor structures to 
 date and the mechanism behind it still remains a mystery. Here we report o
 n two factors\; lipid incubation time and protein concentration and invest
 igate three different lipid systems\; monoolein (MO)\, phytantriol (PT) an
 d phytanoyl ethanomide (PE)\, which influenced the uptake of the Dopamine 
 2 long (D2L) receptor into the lipid structure. We show reasons why the D2
 L receptor has proven to be difficult to crystallize in the commercial cub
 ic phase lipid\, MO\, and show why we need to develop novel crystallizatio
 n media.\n\nhttps://events01.synchrotron.org.au/event/3/contributions/704/
LOCATION: NCSS Exhibition Area
URL:https://events01.synchrotron.org.au/event/3/contributions/704/
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