User Meeting 2022

Recognition and Separation of chiral molecules using Chiral Fluorescent Coordination Cages.

Not scheduled

1m

Hybrid

Poster Chemistry, Catalyses & Soft Matter Poster

Speaker

Ms Diksha Sawant (Monash University)

Description

Chirality, a universal phenomenon, is an intrinsic part of human life. Many major and essential components of a living body including amino acids, sugars, polysaccharides, proteins, and nucleic acids are fundamentally made up of optically active components. It is a well-established fact that the separation of these enantiomers is quite difficult owing to their similar physical and chemical properties in an achiral environment. However, as these enantiomers exhibit different biological and pharmacological activities, their separation still remains to be of great importance to the pharmaceutical industry, food industry, agrochemical industry, fragrances, flavours, etc. Owing to the high surface area, well-defined pore structure, and tuneable pore size, porous materials like coordination cages and polymers are promising candidates in the separation of chiral molecules.
The Turner group at Monash University has been involved in developing new synthetic routes to enantiopure coordination polymers and cage complexes. These supramolecular systems are the harmonious result of serendipity and rational design. With chirality induced by the amino acid groups, a range of compounds with varying dimensions, sizes, and geometry can be synthesized with a variety of potential fluorescent cores. Explicitly focussing on diphthalimide-derived ligands with fluorescent cores, the properties of the resulting cages can be altered by changing the length and other properties of the core, the amino acids, and the metal involved.
This presentation illustrates the basis behind the design of these predicted cages and their fluorescent studies.